The Experimental Immunology and Cell Therapy Division is headed by Evelyn Ullrich, MD, Professor of Cellular Immunology, and includes preclinical and translational research projects as well as education and training in the field of immunology .
Preclinical research projects focus on the investigation of complex interactions in malignant diseases, immunodeficiencies as well as in stem cell transplantation and infectious complications. Our projects include molecular and functional characterization of cellular components of the immune system with emphasis on subsets of T cells, natural killer (NK) cells, cytokine-induced killer (CIK) cells and innate lymphoid cells (ILCs). Transcriptome and proteome analyses at single cell level combined with advanced model systems for live cell imaging provide in-depth understanding of molecular and Translational research aims to develop innovative cell-based immunotherapies. Viral and non-viral technologies for the generation of CAR engineered immune cell products are optimized in a broad range of in vitro/in vivo models. The foundations are laid for GMP-compliant manufacturing and clinical application of genetically modified cell therapies and combinatorial treatment concepts.
Artificial intelligence (AI) and machine learning (ML) technologies for data analysis, design and prediction will be applied to tailor immune cell therapies to specific needs and patients, thereby leading to the next level of development and translation of personalized medicine.
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Paper Award by the German Society for Gene Therapy (DG-GT)
July 2024The recent work by Tobias Bexte on “Engineering of potent CAR NK cells using non-viral Sleeping Beauty transposition from minimalistic DNA vectors“ from the research group… -
Wenn die eigenen Zellen den Krebs besiegen
April 2024Ullrich Lab in the series “Research in Hessen” - with the topic of cell therapy - on 9 April 2024: CAR-T-Zell-Therapie (hessenschau.de)
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28th-30th August 2024Frankfurt
Frankfurt Cancer Conference
The Frankfurt Cancer Conference is a three-day on-site meeting of internationally leading cancer researchers as well as junior scientists and clinical oncologists. The main… -
16th-18th October 2024Lyon
NK/ILC Symposium 2024
The NK/ILC Symposium traditionally takes place in Germany each year, initiated by the Study Group “NK cells and ILCs” of the German Society for Immunology (DGFI). -
6th September 2024Freiburg
Symposium “Intelligent Oncology – The Potential Of AI To Control Cancer“
Bringing together experts from various disciplines to explore the latest advances in AI-assisted cancer research. The Symposium “Intelligent Oncology – The Potential Of AI…
Contact
HEAD
Prof. Dr. med. Evelyn Ullrich
evelyn | ullrichlab.de
+49 69 6301 83000
SCIENTIFIC PROJECT COORDINATION
Dr.rer.nat. Thorsten Diegisser
diegisser | med.uni-frankfurt.de
+49 151 150 96319
LABORATORY
Franziska Ganß
franziska.ganss | med.uni-frankfurt.de
+49 69 6301 80651 (Office)
+49 69 6301 80648 (Laboratory)
+49 151 171 90472